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Worldmeds

Ibuprofen

イブプロフェン

INN: Ibuprofen

NSAID (Non-Steroidal Anti-Inflammatory Drug)Published

Last updated: 3/14/2026

Mechanism of Action

JA日本語

シクロオキシゲナーゼ(COX-1およびCOX-2)を阻害し、プロスタグランジンの合成を抑制することで、抗炎症・鎮痛・解熱作用を発揮します。

ENEnglish

Inhibits cyclooxygenase (COX-1 and COX-2), suppressing prostaglandin synthesis to produce anti-inflammatory, analgesic, and antipyretic effects.

Side Effects

JA日本語

胃腸障害(胃痛、悪心、下痢)、腎機能障害、浮腫、めまい。長期使用で消化性潰瘍のリスク。

ENEnglish

Gastrointestinal disorders (stomach pain, nausea, diarrhea), renal impairment, edema, dizziness. Risk of peptic ulcer with long-term use.

Contraindications

JA日本語

消化性潰瘍のある患者。重篤な血液異常のある患者。重篤な肝・腎障害のある患者。妊娠後期の女性。

ENEnglish

Patients with peptic ulcer. Patients with severe blood disorders. Patients with severe hepatic or renal impairment. Women in late pregnancy.